cardiachypertrophy相关论文
Harmine is a β-carboline alkaloid isolated from Banisteria caapi and Peganum harmala L with various pharmacological act......
Cardiac hypertrophy is a common adaptive response to a variety of stimuli,but prolonged hypertrophy leads to heart failu......
持续性的心肌肥厚会使心脏受损和心功能减弱，最终导致心脏衰竭甚至死亡。微小RNA（microRNA，miRNA）是生物体内重要的调控因子，可参与心肌......
Zonisamide alleviates cardiac hypertrophy in rats by increasing Hrd1 expression and inhibiting endop
Antiepileptic drug zonisamide has been shown to be curative for Parkinson\'s disease (PD) through increasing HMG-CoA r......
Glucagon-like peptide-1 attenuates cardiac hypertrophy via the AngⅡ/AT1R/ACE2 and AMPK/mTOR/p70S6K p
Glucagon-like peptide-1(GLP-1),a novel type of glucose-lowering agent,has been reported to exert cardioprotective effect......
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To investigate the effect of Yiqi Wenyang (YQWY) decoction on reversing cardiac hypertrophy induced by the transverse ao......
Chronic intermittent hypoxia impairs cardiac autophagy and induces cardiac hypertrophy through the 5
目的 Autophagy is tightly regulated to maintain heart homeostasis.Impaired autophagy is closely associated with patholog......
Andrographolide inhibit isoproterenol-induced myocardial hypertrophy in rats by reducing the excessi
Aim: To explore the inhibition effect of andrographolide (AP) on myocardial hypertrophy induced by isoproterenol (Iso), ......
Aims:Nogo-B plays crucial roles in vascular remodeling.However,its roles in cardiac remodeling remain unclear.The aim of......
Aim: Cardiac hypertrophy is regarded as a clinical determinant of heart failure.The average age of cardiac hypertrophy o......
EFFECTS OF DAURISOLINE ON EARLY AFTERDEPOLARIZATIONS INDUCED BY DOFETILIDE AND ON L-TYPE CALCIUM CUR
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Cardioprotective effect of selective slgma-1 receptor agonist SA4503 in transverse aortic constricti
Aim: We previously reported that a SSRI, fluvoxamine with high affinity for sigma-1 receptor, ameliorates transverse aor......
Myocardial expression of Foxp3 in cardiac hypertrophy induced by isoprenaline and effect of triptoli
Aim: Inflammation and immune have been demonstrated to be involved in the pathophysiological process of cardiac hypertro......
Introduction: Nicotinamide phosphoribosyltransferase(Nampt)is a crucial coenzyme in cellular redox reactions.Inside the ......
Introduction: Cyclins/retinoblastoma protein(pRb)pathway participates in cardiomyocyte hypertrophy.Cyclins and cyclin ki......
Aim To explore the role of transcription factor Foxp3 and the regulating effect of triptolide (TP) in the progression of......
Proteasome inhibition ameliorates cardiomyocyte hypertrophy through GSK-3α/β pathway in primary neon
Aim Previous studies showed that the inhibition of proteasome activity could significantly improve cardiac hypertrophy, ......
Calcium ion influx through CaV1.2 calcium channel is essential for the cardiac excitation contraction coupling and dysfu......
Objective: To Explore the Role of GRK5 in sustained β AR-stimulated increased levels of oxidative stress.Methods:Male S......
Proteasome inhibition ameliorates cardiomyocyte hypertrophy through GSK-3α/β pathway in primary neon
Objective Previous studies showed that the inhibition of proteasome activity could significantly improve cardiac hypertr......
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Regulator of G-protein signaling 10 negatively regulates cardiac remodeling by blocking MEK-ERK1/2 s
Regulator of G-protein signaling 10 (RGS10) is an important member of the RGS family and produces biological effects in ......
Temporal expressions of cell cycle regulators mRNA during hypertrophic process of H9c2 cells induced
Aim: To observe the mRNA expressions of cell cycle regulators at different time point during the hypertrophic process of......
Temporal expressions of cell cycle regulators mRNA during hypertrophic process of H9c2 rat cardiomyo
Aim: To observe the mRNA expressions of cell cycle regulators at different time point during the hypertrophic process of......
Aim: Cardiac hypertrophy is a primary predicator of progressive heart disease that often results in heart failure.This s......
Functional Changes of TREK-1 Potassium Channel in Ventricular Myocytes During Rat Cardiac Hypertroph
Aim: Two pore domain potassium channel TREK-1 has been shown to present in the mammalian heart, but the role of TREK-1 i......
Sodium tanshinone ⅡA sulfonate (STS) is a water-soluble derivative of tanshinone ⅡA, the major lipophilic component ex......
Cardiac hypertrophy is initially compensatory, but it ultimately leads to heart failure.An increasing amount of evidence......
AIM Cardiac hypertrophy is regarded as a clinical determinant of heart failure.The average age of cardiac hypertrophy on......
Basal autophagy is tightly regulated by transcriptional and epigenetic factors to maintain cellular homeostasis.Dysregul......
Objective:Cardiac hypertrophy is an adaptive reaction of the heart against cardiac overloading,but continuous cardiac hy......
Familial Atrial Enlargement,Conduction Disorder and Symmetric Cardiac Hypertrophy Are Early Signs of
PRKAG2 cardiac syndrome(PS)is a rare inherited disease due to PRKAG2 gene mutation and characterized by Wolff-Parkinson-......
Effect of the Shensong Yangxin Capsule on Energy Metabolism in Angiotensin II-Induced Cardiac Hypert
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Objective:To investigate the effect of astragaloside IV on cardiac hypertrophy and its regulation on autophagy.Methods:F......
MicroRNA-214 contributes to Ang Ⅱ-induced cardiac hypertrophy by targeting SIRT3 to provoke mitochon
Reduction of expression and activity of sirtuin 3 (SIRT3) contributes to the pathogenesis of cardiomyopathy via inducing......
The bromodomain and extraterminal(BET)family member BRD4 is pivotal in the pathogen-esis of cardiac hypertrophy.BRD4 ind......
心肌肥厚是各种心血管疾病共同的病理过程,最终发展为心力衰竭.本文旨在研究不同品系小鼠在肥大刺激后表现出的不同病理学特征.通......
Background: Hyperglycemia in diabetic mothers enhances the risk of fetal cardiac hypertrophy during gestation.Howeve......
The roles of transient receptor potential channels in the development of pathological cardiac hypert
Transient receptor potential (TRP) channels are a large family of non-selective cation channels,including a total of......
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Buckwheat Rutin Exhibited inhibitory effect on Angiotensin Ⅱ-induced Proliferation of Fibroblasts by
Studies have found that buckwheat rutin could inhibit proliferation of cardiac fibroblasts induced by angiotensin II, bu......
